Selected Personalized Medicine Drugs and Relevant Genes as of May 2014
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چکیده
Sodium phenylacetate & sodium benzoate (Ammonul) NAGS; CPS; ASS; OTC; ASL; ARG Urea cycle disorders: Urea cycle disorders can result from decreased activity of any of the following enzymes: N-acetylglutamate synthetase (NAGS), carbamyl phosphate synthetase (CPS), argininosuccinate synthetase (ASS), ornithine transcarbamylase (OTC), argininosuccinate lyase (ASL), or arginase (ARG).Sodium phenylacetate and sodium benzoate are metabolically active compounds that can serve as alternatives to urea for the excretion of waste nitrogen.
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